Unlocking AI-engineered medicines: from implementation to success.
Chem Together #18 is poised to delve into groundbreaking subjects at the intersection of artificial intelligence and pharma.
We will focus on two key areas: leveraging AI for vaccine design to enhance the stability and expression of viral spikes, and the imperative of digital transformation in biomedicine. Through practical strategies and real-life case studies, attendees will gain insights into accelerating drug discovery and optimizing operations with AI integration.
These discussions promise to provide invaluable insights into the potential of AI-engineered medicines and the pathway to their successful implementation.
Programme
15.30: Doors open and registration
16.00: Word of welcome by ACN
16.05: Dr. Jarek Juraszek - Avidicure / ex-Janssen
16.35: Dr. Volodimir Olexiouk – BioLizard
17.05: Conclusion, networking, drinks and bites
18.00: End of the event
Meet the speakers
🗣️ Dr. Jarek Juraszek – Director Discovery Data Science at Avidicure / ex-Principal Scientist at Janssen
“Improving vaccine design with AI-based protein engineering”
Over the past few years, my focus has been on leveraging AI models to generate protein mutations that enhance stability and expression. This aspect is crucial in viral vaccine design, particularly for using viral spikes as immunogens. These spikes are typically metastable and tend to have low expression levels. Our work has demonstrated that even relatively straightforward convolutional AI models outperform the traditional physics-based methods prevalent in protein design. We've successfully identified stabilizing mutations for hundreds of mutants across various targets, and developed immunogens for in vivo studies, marking significant progress in the field.
🗣️ Dr. Volodimir Olexiouk - Team Lead AI and Advanced Analytics at BioLizard
“In today's rapidly evolving biomedicine landscape, digital transformation is essential for biotech and biopharma”
Amidst the hype, practicality is crucial. We will present a practical roadmap to guide successful digital transformation, emphasizing data management and AI and punctuated by real-life case studies that showcase tangible benefits such as accelerated drug discovery and optimized operations. Drawing on BioLizard’s experience in supporting biotech and biopharma in both data-driven strategy and implementation of digital technologies, we will demonstrate the importance of adopting a data-centric business strategy from data collection and storage to implementation of ML to integrate complex biological data - to ultimately deliver on the promise of data-driven technologies.
The event is free of charge thanks to ChemistryNL and all the ACN members.
