Ultrasound can give a profound insight into facial anatomy. The use of it increases safety in injectable treatments by reducing the hazards of technical complications and adverse events. Our Dermatologic Ultrasound (DUS) guide is a systematic approach to ultrasound examination of the face. Using DUS guide the performing physician can visualize the important structures and pinpoint the preferred location of the planned injectable treatment. Vessels, relevant muscles and bony structures are easily appreciated and can be avoided. The volume and type of injectable can be determined. Also, injectables already in situ can be assessed. All of this will produce a safer and better outcome.